Physical Measurements in Living Systems – measuring time-dependent cell mechanics in the presence o
TU Dresden | Sommersemester 2023
Physical Measurements in Living Systems
measuring time-dependent cell mechanics
Elective MSc Physics of Life
Title: Physical measurements in living systems – measuring time-dependent cell mechanics in the presence of active stress
Teacher: Dr. Elisabeth Fischer-Friedrich
Track: Experimental Biological Physics
Course work: 2 SWS lecture, 2 SWS exercise
Location: Tatzberg 47-49, Biotec, room E05
Time: Friday, lecture: 9:20 am, seminar: 11:10 am
Term: Summer term
- The students will learn the basics of linear elasticity theory and viscoelastic models that are relevant for the field of cell mechanics. This will be a foundation for understanding analysis approaches of cell-mechanical models.
- We will review molecular structures in the cell that dominate cell mechanics.
- The students will hear about different methods for cell-mechanical measurements (indentation with AFM, parallel plate assay, bead-tracking micro-rheology, magnetic oil droplets, magnetic tweezers) and discuss the analysis pathways and published results.
- In addition, I will point out limitations of different experimental setups and alternative interpretation approaches as well as controversies in the field.
Requirements: knowledge of PDEs and higher calculus
Number of participants: up to 30 people
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