Biomedical Laser Systems and Optogenetics

Lectures are given Wednesday, 09:20-10:50, Room  BAR/I88

Biomedical systems engineering is a multidisciplinary field of engineering and has a direct impact on human well-being. The aim of the lecture Biomedical Laser Systems and Optogenetics is to discuss laser-optical methods and systems for the early detection, diagnosis, therapy and rehabilitation of diseases.

Optogenetics is a combination of methods of optics and genetics. It deals with real-time how holographic laser techniques can be used to control genetically modified cells. Adaptive microscopy using deep neural networks enable 3D imaging into deep tissue layers. Furthermore, of the brain, Brillouin microscopy for contactless sensing with light for cancer diagnosis and needle-thin lensless fiber endoscopes for diagnostics and therapy gentle examinations and stimulations are covered in the lecture.

Biomedical Laser Systems and Optogenetics is part of the modules:
„Photonische Messsystemtechnik“. (V/Ü/P: 2/0/0), 9. Semester
And
"Sensoren u. Messsysteme-Vertiefung" (3/0/2), 9. Semester
And the subsidiary and application subject
COMPUTATIONAL LASER METROLOGY (INF-D-920)

Topics

• Modelling Light and Simulating Light Propagation (Ray & Wave optics)
• Imaging Systems (Lenses, PSF, Aberrations, Resolution limit)
• Wave front measurement (Holography, image based, Neural Networks)
• Wave front manipulation (programmable optics)
• Light Matter interaction (absorption, scattering, fluorescence)
• advanced microscopy (PSF engineering, Light Sheet, Scatter plate/diffusor, nonlinear)
• Endoscopy (Boroscopes, Cam on Tip, SM Fiber based)
• Optical Fibers
• Advanced Fiber Endoscopes I (Holographic Endoscopes)
• Advanced Fiber Endoscopes II (NN based Endoscopes)
• Cell Tomography (Tomographic reconstruction, optical traps)
• Optogenetics
• Brillouin spectroscope and microscopy